By Cesar Collado

Neuropathic Pain or nerve pain – is a type of chronic pain resulting from nerve damage in the central nervous due to injured or chronic disease. It can have a significant negative impact on quality of life.

For decades, patients suffer from neuropathic or muscle pain have relied on various treatments to alleviate pain.  Some are analgesics and anesthetics; and others are counter irritants that create a temporary hot and/or cold sensation. These sensations can interrupt signals to the brain, essentially distracting the brain from pain.  Peripheral neuropathy is a type of neuropathic pain affecting the peripheral nerves, meaning nerves beyond the brain and spinal cord. Peripheral nerve damage may impair sensation, movement, or gland or organ function. Neuropathy can affecting motor, sensory, or autonomic nerves and result in symptoms including pain, soreness, numbing, or tingling.

Causes of peripheral neuropathy are not precisely known, however, current contributors include:

There is no medicine that specifically addresses neuropathic pain.  Treatment includes a range of options, often practiced by referred specialists:

  • Pharmaceuticals:  Physicians may attempt to manage utilizing anticonvulsant, antidepressant, anti-inflammatory medications (NSAIDs), occasional (often controversial) use of opioid medicines, and Botulism injection (at pain sites)  
  • Acupuncture
  • Chiropractic Medicine
  • Massage Therapy
  • Physical Therapy
  • Electrical Stimulation

Self-Treatment and Over the Counter (OTC) Pain Management

Because of the severity and complexity of neuropathic pain, patients often utilize OTC and Nutritional Supplements to aid in pain management.  Many OTC mediations have been utilized for decades or longer.

These OTC topical products include one or several of these active ingredients:

  • Salicylate (Analgesic):   A salt or ester of salicylic acid. Salicylates are found naturally in some plants (such as white willow bark and wintergreen leaves) and are thought to protect the plant against insect damage and disease. Aspirin is a derivative of salicylic acid 
  • NSAIDS: Non-Steroidal Anti-Inflammatory Drugs (Analgesics):  include Ibuprofen, naproxen, and other prescription NSAID medications.
  • Lidocaine (Anesthetic): A numbing agent.
  • Camphor: (Counter-irritant):  An organic compound  extracted from the wood of camphor trees in Asia. It can be used topically to relieve pain, irritation, and itching. 
  • Menthol: (Counter-irritant): A compound naturally found in mint plants such as peppermint and spearmint. It gives a cooling sensation. It is often used to relieve minor pain and irritation and prevent infection.
  • Essential Oils: ginger, cypress, sandalwood, black Pepper, clove, Clary sage, Juniper, arnica, and lemongrass.  These are commonly used for their antioxidant effects. 
  • Capsaicin (Analgesic) Capsaicin is a chili pepper extract with analgesic properties
  • CBD products (Cannabidiol).  These products claim to provide the compound Cannabidiol, derived from the marijuana plant minus tetrahydrocannabinol, or THC, which is the substance that that produces the “high” from marijuana.  In the case of CBD products, the marketing has been far ahead of the science or legality of such products.  In fact, they remain prohibited in athletes and any other occupation requiring drug testing.  These products are promoted for a variety of uses without scientific support.

Well known products like Tiger Balm, Icy Hot, Ben Gay, Vicks Vapor Rub, and others geared toward athletic applications are commonly used.

Glutathione and Pain 

Glutathione is known as the body’s “Master Antioxidant.”  Antioxidants are compounds produced both in your body and found in many foods we eat. They help defend your cells from damage caused by potentially harmful molecules known as free radicals.   These free radicals are created when the body suffers oxidative stress.  

Oxidative stress occurs when oxygen in the body splits into single atoms with unpaired electrons. Electrons like to be in pairs, so these atoms, called free radicals, scavenge the body to seek out other electrons so they can become a pair. This causes damage to cells, proteins and DNA. When free radicals accumulate, they cause oxidative stress. This may damage your DNA and other important structures in your cells.  Because glutathione exists within the cells at high levels, it is in the ideal position to combat free radicals in the cell.

CitriSafe Ovation Acetyl Glutathione provides the most bioavailable formulation and highest quality of acetyl glutathione for maximum absorption into the blood stream, coupled with proprietary nanotechnology employing “micro-clusters” to encapsulate the acetyl glutathione to ensure that it does not break down in the gut.  As a result, dosing requirements are lower than the glutathione products found in vitamin stores or online due to improved efficiency in reaching the proper blood levels.  Citrisafe Oral Acetyl Glutathione is physician prescribed and recommended.

Topical Delivery of Glutathione

There are numerous routes of delivery for glutathione.  Oral delivery is the most common delivery mechanisms that delivers nutrients and/or remedies to the body; however, this option employs systemic delivery of the medicine to the body specific location only after it is digested, absorbed, and metabolized.  

Topical delivery is the mechanism through which compounds are absorbed transdermally, through the skin. This is beneficial as it bypasses the digestive system and liver metabolism to enter the blood stream.  Local or topical delivery is often more precise than oral delivery, as the medication can reach the target area without being required to pass through the body’s metabolism.

Local topical delivery is often perceived as optimal by patients  for muscle soreness and neuropathic pain.  It allows the molecule to reach the muscle tissues and nerves nearby where the product is delivered.

CitriSafe Acetyl-Glutathione Balm for Neuropathic, Muscle and Joint Pain

Because Glutathione helps defend your cells from damage caused by potentially harmful molecules known as free radicals.     Oxidative stress occurs naturally during exercise when muscle breakage damages muscle tissue. Because glutathione exists within the cells at high levels, it is in the ideal position to combat free radicals in the cell.  When your metabolism is ramped up, as with exercise, free radicals overwhelm your antioxidant defenses causing damage to cells.  The excessive production of reactive oxygen species (ROS) leads to tissue injury which in turn lead to inflammation. By binding to and eliminating reactive oxygen species ( free radicals that are chemicals containing oxygen), glutathione can diminish oxidative stress and simultaneously alleviate inflammation. ROS increase significantly during environmental stress or heat (exercise). This is why you see faster muscle recovery with the supplementation of glutathione. 

Glutathione also boosts mitochondria performance. Mitochondria are the energy factories of your body and they produce around 90% of your energy. Meaning, glutathione assists cells in creating more energy.  This is why there is often an increase in strength and endurance with glutathione supplementation. The overactive metabolism with regular reduced injuries and the creation of muscle development.

CitriSafe Acetyl Glutathione Balm is delivered in a coconut cream/olive oil base with nano-technology to increase absorption and is a great skin care product. Neuropathic pain is a complex disease not well understood by medicine.  Like many diseases of unknown origin, trial and error is essential to find what remedies provide relief for pain management, if any.  This formulation also is being used on joint, muscle and arthritis pain. It is currently in studies to treat carpal tunnel syndrome and to soothe neuropathy symptoms including numbness, burning, tingling, sensitivity and weakness. 

Customers continue to find new uses every day! 

If you would like to share your story, please comment on this article below.  You can also email me direct at cesarcollado@icloud.com.

About the Author:  Cesar Collado is a former pharmaceutical R&D senior executive, venture capitalist, and seasoned strategy consultant in biotechnology and technology industries in general. He currently works as an advisor to multiple technology start-ups and advises several companies with technology solutions, including companies  that provide healthcare and other services for environmental illness.  Cesar worked with MicroBalance Health Products from 2014-2019, where he had responsibility for strategy, revenues, marketing, and finance, as well as, writing all original content for the company’s newsletters during his tenure.

Cesar is passionate about awareness and treatment of environmental illness as a significant, unmet and misdiagnosed, medical need. He has partnered with Integrative Physicians, Bau-Biologists, Environmental Inspectors, Mold Remediators, HVAC IAQ Specialists, and other professionals to generate educational materials for the environmentally ill.  Cesar currently writes original content for ImmunLytics, Bio-Balance, and CitriSafe: Protocols and Products for a Healthy Life.

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